Includes bibliographical references and index.

Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgement -- 1 Deep Learning and Site-Specific Drug Delivery: The Future and Intelligent Decision Support for Pharmaceutical Manufacturing Science -- 1.1 Introduction -- 1.2 Drug Discovery, Screening and Repurposing -- 1.3 DL and Pharmaceutical Formulation Strategy -- 1.3.1 DL in Dose and Formulation Prediction -- 1.3.2 DL in Dissolution and Release Studies -- 1.3.3 DL in the Manufacturing Process -- 1.4 Deep Learning Models for Nanoparticle-Based Drug Delivery -- 1.4.1 Nanoparticles With High Drug Delivery Capacities Using Perturbation Theory -- 1.4.2 Artificial Intelligence and Drug Delivery Algorithms -- 1.4.3 Nanoinformatics -- 1.5 Model Prediction for Site-Specific Drug Delivery -- 1.5.1 Prediction of Mode and a Site-Specific Action -- 1.5.2 Precision Medicine -- 1.6 Future Scope and Challenges -- 1.7 Conclusion -- References -- 2 Role of Deep Learning, Blockchain and Internet of Things in Patient Care -- 2.1 Introduction -- 2.2 IoT and WBAN in Healthcare Systems -- 2.2.1 IoT in Healthcare -- 2.2.2 WBAN -- 2.2.2.1 Key Features of Medical Networks in the Wireless Body Area -- 2.2.2.2 Data Transmission &amp -- Storage Health -- 2.2.2.3 Privacy and Security Concerns in Big Data -- 2.3 Blockchain Technology in Healthcare -- 2.3.1 Importance of Blockchain -- 2.3.2 Role of Blockchain in Healthcare -- 2.3.3 Benefits of Blockchain in Healthcare Applications -- 2.3.4 Elements of Blockchain -- 2.3.5 Situation Awareness and Healthcare Decision Support with Combined Machine Learning and Semantic Modeling -- 2.3.6 Mobile Health and Remote Monitoring -- 2.3.7 Different Mobile Health Application with Description of Usage in Area of Application -- 2.3.8 Patient-Centered Blockchain Mode -- 2.3.9 Electronic Medical Record -- 2.3.9.1 The Most Significant Barriers to Adoption Are.

2.3.9.2 Concern Regarding Negative Unintended Consequences of Technology -- 2.4 Deep Learning in Healthcare -- 2.4.1 Deep Learning Models -- 2.4.1.1 Recurrent Neural Networks (RNN) -- 2.4.1.2 Convolutional Neural Networks (CNN) -- 2.4.1.3 Deep Belief Network (DBN) -- 2.4.1.4 Contrasts Between Models -- 2.4.1.5 Use of Deep Learning in Healthcare -- 2.5 Conclusion -- 2.6 Acknowledgments -- References -- 3 Deep Learning on Site-Specific Drug Delivery System -- 3.1 Introduction -- 3.2 Deep Learning -- 3.2.1 Types of Algorithms Used in Deep Learning -- 3.2.1.1 Convolutional Neural Networks (CNNs) -- 3.2.1.2 Long Short-Term Memory Networks (LSTMs) -- 3.2.1.3 Recurrent Neural Networks -- 3.2.1.4 Generative Adversarial Networks (GANs) -- 3.2.1.5 Radial Basis Function Networks -- 3.2.1.6 Multilayer Perceptron -- 3.2.1.7 Self-Organizing Maps -- 3.2.1.8 Deep Belief Networks -- 3.3 Machine Learning and Deep Learning Comparison -- 3.4 Applications of Deep Learning in Drug Delivery System -- 3.5 Conclusion -- References -- 4 Deep Learning Advancements in Target Delivery -- 4.1 Introduction: Deep Learning and Targeted Drug Delivery -- 4.2 Different Models/Approaches of Deep Learning and Targeting Drug -- 4.3 QSAR Model -- 4.3.1 Model of Deep Long-Term Short-Term Memory -- 4.3.2 RNN Model -- 4.3.3 CNN Model -- 4.4 Deep Learning Process Applications in Pharmaceutical -- 4.5 Techniques for Predicting Pharmacotherapy -- 4.6 Approach to Diagnosis -- 4.7 Application -- 4.7.1 Deep Learning in Drug Discovery -- 4.7.2 Medical Imaging and Deep Learning Process -- 4.7.3 Deep Learning in Diagnostic and Screening -- 4.7.4 Clinical Trials Using Deep Learning Models -- 4.7.5 Learning for Personalized Medicine -- 4.8 Conclusion -- Acknowledgment -- References -- 5 Deep Learning and Precision Medicine: Lessons to Learn for the Preeminent Treatment for Malignant Tumors.

5.1 Introduction -- 5.2 Role of DL in Gene Identification, Unique Genomic Analysis, and Precise Cancer Diagnosis -- 5.2.1 Gene Identification and Genome Data -- 5.2.2 Image Diagnosis -- 5.2.3 Radiomics, Radiogenomics, and Digital Biopsy -- 5.2.4 Medical Image Analysis in Mammography -- 5.2.5 Magnetic Resonance Imaging -- 5.2.6 CT Imaging -- 5.3 DL in Next-Generation Sequencing, Biomarkers, and Clinical Validation -- 5.3.1 Next-Generation Sequencing -- 5.3.2 Biomarkers and Clinical Validation -- 5.4 DL and Translational Oncology -- 5.4.1 Prediction -- 5.4.2 Segmentation -- 5.4.3 Knowledge Graphs and Cancer Drug Repurposing -- 5.4.4 Automated Treatment Planning -- 5.4.5 Clinical Benefits -- 5.5 DL in Clinical Trials-A Necessary Paradigm Shift -- 5.6 Challenges and Limitations -- 5.7 Conclusion -- References -- 6 Personalized Therapy Using Deep Learning Advances -- 6.1 Introduction -- 6.2 Deep Learning -- 6.2.1 Convolutional Neural Networks -- 6.2.2 Autoencoders -- 6.2.3 Deep Belief Network (DBN) -- 6.2.4 Deep Reinforcement Learning -- 6.2.5 Generative Adversarial Network -- 6.2.6 Long Short-Term Memory Networks -- References -- 7 Tele-Health Monitoring Using Artificial Intelligence Deep Learning Framework -- 7.1 Introduction -- 7.2 Artificial Intelligence -- 7.2.1 Types of Artificial Intelligence -- 7.2.1.1 Machine Intelligence -- 7.2.1.2 Types of Machine Intelligence -- 7.2.2 Applications of Artificial Intelligence -- 7.2.2.1 Role in Healthcare Diagnostics -- 7.2.2.2 AI in Telehealth -- 7.2.2.3 Role in Structural Health Monitoring -- 7.2.2.4 Role in Remote Medicare Management -- 7.2.2.5 Predictive Analysis Using Big Data -- 7.2.2.6 AI's Role in Virtual Monitoring of Patients -- 7.2.2.7 Functions of Devices -- 7.2.2.8 Clinical Outcomes Through Remote Patient Monitoring -- 7.2.2.9 Clinical Decision Support.

7.2.3 Utilization of Artificial Intelligence in Telemedicine -- 7.2.3.1 Artificial Intelligence-Assisted Telemedicine -- 7.2.3.2 Telehealth and New Care Models -- 7.2.3.3 Strategy of Telecare Domain -- 7.2.3.4 Role of AI-Assisted Telemedicine in Various Domains -- 7.3 AI-Enabled Telehealth: Social and Ethical Considerations -- 7.4 Conclusion -- References -- 8 Deep Learning Framework for Cancer Diagnosis and Treatment -- 8.1 Deep Learning: An Emerging Field for Cancer Management -- 8.2 Deep Learning Framework in Diagnosis and Treatment of Cancer -- 8.3 Applications of Deep Learning in Cancer Diagnosis -- 8.3.1 Medical Imaging Through Artificial Intelligence -- 8.3.2 Biomarkers Identification in the Diagnosis of Cancer Through Deep Learning -- 8.3.3 Digital Pathology Through Deep Learning -- 8.3.4 Application of Artificial Intelligence in Surgery -- 8.3.5 Histopathological Images Using Deep Learning -- 8.3.6 MRI and Ultrasound Images Through Deep Learning -- 8.4 Clinical Applications of Deep Learning in the Management of Cancer -- 8.5 Ethical Considerations in Deep Learning-Based Robotic Therapy -- 8.6 Conclusion -- Acknowledgments -- References -- 9 Applications of Deep Learning in Radiation Therapy -- 9.1 Introduction -- 9.2 History of Radiotherapy -- 9.3 Principal of Radiotherapy -- 9.4 Deep Learning -- 9.5 Radiation Therapy Techniques -- 9.5.1 External Beam Radiation Therapy -- 9.5.2 Three-Dimensional Conformal Radiation Therapy (3D-CRT) -- 9.5.3 Intensity Modulated Radiation Therapy (IMRT) -- 9.5.4 Image-Guided Radiation Therapy (IGRT) -- 9.5.5 Intraoperative Radiation Therapy (IORT) -- 9.5.6 Brachytherapy -- 9.5.7 Stereotactic Radiosurgery (SRS) -- 9.6 Different Role of Deep Learning with Corresponding Role of Medical Physicist -- 9.6.1 Deep Learning in Patient Assessment -- 9.6.1.1 Radiotherapy Results Prediction.

9.6.1.2 Respiratory Signal Prediction -- 9.6.2 Simulation Computed Tomography -- 9.6.3 Targets and Organs-at-Risk Segmentation -- 9.6.4 Treatment Planning -- 9.6.4.1 Beam Angle Optimization -- 9.6.4.2 Dose Prediction -- 9.6.5 Other Role of Deep Learning in Corresponds with Medical Physicists -- 9.7 Conclusion -- References -- 10 Application of Deep Learning in Radiation Therapy -- 10.1 Introduction -- 10.2 Radiotherapy -- 10.3 Principle of Deep Learning and Machine Learning -- 10.3.1 Deep Neural Networks (DNN) -- 10.3.2 Convolutional Neural Network -- 10.4 Role of AI and Deep Learning in Radiation Therapy -- 10.5 Platforms for Deep Learning and Tools for Radiotherapy -- 10.6 Radiation Therapy Implementation in Deep Learning -- 10.6.1 Deep Learning and Imaging Techniques -- 10.6.2 Image Segmentation -- 10.6.3 Lesion Segmentation -- 10.6.4 Computer-Aided Diagnosis -- 10.6.5 Computer-Aided Detection -- 10.6.6 Quality Assurance -- 10.6.7 Treatment Planning -- 10.6.8 Treatment Delivery -- 10.6.9 Response to Treatment -- 10.7 Prediction of Outcomes -- 10.7.1 Toxicity -- 10.7.2 Survival and the Ability to Respond -- 10.8 Deep Learning in Conjunction With Radiomoic -- 10.9 Planning for Treatment -- 10.9.1 Optimization of Beam Angle -- 10.9.2 Prediction of Dose -- 10.10 Deep Learning's Challenges and Future Potential -- 10.11 Conclusion -- References -- 11 Deep Learning Framework for Cancer -- 11.1 Introduction -- 11.2 Brief History of Deep Learning -- 11.3 Types of Deep Learning Methods -- 11.4 Applications of Deep Learning -- 11.4.1 Toxicity Detection for Different Chemical Structures -- 11.4.2 Mitosis Detection -- 11.4.3 Radiology or Medical Imaging -- 11.4.4 Hallucination -- 11.4.5 Next-Generation Sequencing (NGS) -- 11.4.6 Drug Discovery -- 11.4.7 Sequence or Video Generation -- 11.4.8 Other Applications -- 11.5 Cancer -- 11.5.1 Factors.

Description based on online resource; title from digital title page (viewed on October 18, 2022).

Deep Learning for Targeted Treatments describes the importance of the deep learning framework for patient care, disease imaging/detection, and health management. Since deep learning can and does play a major role in a patient's healthcare management by controlling drug delivery to targeted tissues or organs, the main focus of the book is to leverage the various prospects of the DL framework for targeted therapy of various diseases. In terms of its industrial significance, this general-purpose automatic learning procedure is being widely implemented in pharmaceutical healthcare.

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